Shigyo2025FPTPC

Title

From Play to Precision Care: Clinical Telegaming Biomarkers to Evaluate Medication Efficacy for Improving Multiple Sclerosis Patients' Quality of Life
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Authors

Kento Shigyo

Affiliations

Brain Health Alliance Virtual Institute, Ladera Ranch, CA 92694 USA

Abstract

Multiple sclerosis (MS) is a chronic autoimmune disease that affects motor, sensory, cognitive, and social functioning, often diminishing patients' quality of life. Disease-modifying therapies (DMTs) aim to slow disease progression, yet evaluating their real-world effectiveness remains challenging due to the limitations of brief, clinic-based assessments. This research proposes the use of clinical telegaming as a home-based assessment platform to generate digital biomarkers reflecting motor-sensory and social-behavioral functioning in everyday contexts. By capturing fine-grained gameplay interaction data, the proposed system aims to support precision care by enabling timely, ecologically valid evaluation of medication efficacy and quality-of-life outcomes for individuals living with MS.

KeyPhrases

Multiple sclerosis, clinical telegaming, digital biomarkers, precision care, quality of life.

Dates

Created 2025-09-16, presented 2025-10-09, updated 2025-12- 17, published 2025-12-17.

Citation

Brainiacs Journal 2025 Volume 6 Issue 3 Edoc B3D757EF9
DOI: 10.48085/B3D757EF9
NPDS: LINKS/Brainiacs/Shigyo2025FPTPC